Try questioning whether your epistemic humility is just fear by another name.
Imagine no one else knew the answer, and it was your job to figure it out. How does that feel?
If it feels scary, that’s a good sign: stay with that, and keep imagining it, and start trying to figure it out as if it were your only option.
Because, actually, all the progress and decisions in the world are made by people not that much smarter than you, if at all, and either you can at least sorta try to figure it out or we’re really fucked.